Percin
Brand names,
Percin
Analogs
Percin
Brand Names Mixture
Percin
Chemical_Formula
C19H24N2O3
Percin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Percin
fda sheet
Percin
msds (material safety sheet)
Percin
Synthesis Reference
No information avaliable
Percin
Molecular Weight
328.406 g/mol
Percin
Melting Point
195-196 oC
Percin
H2O Solubility
20 mg/ml (HCl salt)
Percin
State
Solid
Percin
LogP
2.868
Percin
Dosage Forms
Liquid; Tablet
Percin
Indication
For the management of hypertension.
Percin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Percin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Percin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Percin
Patient Information
Percin
Organisms Affected
Humans and other mammals