Zonazide
Brand names,
Zonazide
Analogs
Zonazide
Brand Names Mixture
Zonazide
Chemical_Formula
C19H24N2O3
Zonazide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Zonazide
fda sheet
Zonazide
msds (material safety sheet)
Zonazide
Synthesis Reference
No information avaliable
Zonazide
Molecular Weight
328.406 g/mol
Zonazide
Melting Point
195-196 oC
Zonazide
H2O Solubility
20 mg/ml (HCl salt)
Zonazide
State
Solid
Zonazide
LogP
2.868
Zonazide
Dosage Forms
Liquid; Tablet
Zonazide
Indication
For the management of hypertension.
Zonazide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Zonazide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Zonazide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Zonazide
Patient Information
Zonazide
Organisms Affected
Humans and other mammals