Tubazid
Brand names,
Tubazid
Analogs
Tubazid
Brand Names Mixture
Tubazid
Chemical_Formula
C19H24N2O3
Tubazid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tubazid
fda sheet
Tubazid
msds (material safety sheet)
Tubazid
Synthesis Reference
No information avaliable
Tubazid
Molecular Weight
328.406 g/mol
Tubazid
Melting Point
195-196 oC
Tubazid
H2O Solubility
20 mg/ml (HCl salt)
Tubazid
State
Solid
Tubazid
LogP
2.868
Tubazid
Dosage Forms
Liquid; Tablet
Tubazid
Indication
For the management of hypertension.
Tubazid
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tubazid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tubazid
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tubazid
Patient Information
Tubazid
Organisms Affected
Humans and other mammals