Inah
Brand names,
Inah
Analogs
Inah
Brand Names Mixture
Inah
Chemical_Formula
C19H24N2O3
Inah
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Inah
fda sheet
Inah
msds (material safety sheet)
Inah
Synthesis Reference
No information avaliable
Inah
Molecular Weight
328.406 g/mol
Inah
Melting Point
195-196 oC
Inah
H2O Solubility
20 mg/ml (HCl salt)
Inah
State
Solid
Inah
LogP
2.868
Inah
Dosage Forms
Liquid; Tablet
Inah
Indication
For the management of hypertension.
Inah
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Inah
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Inah
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Inah
Patient Information
Inah
Organisms Affected
Humans and other mammals