Pelazid
Brand names,
Pelazid
Analogs
Pelazid
Brand Names Mixture
Pelazid
Chemical_Formula
C19H24N2O3
Pelazid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Pelazid
fda sheet
Pelazid
msds (material safety sheet)
Pelazid
Synthesis Reference
No information avaliable
Pelazid
Molecular Weight
328.406 g/mol
Pelazid
Melting Point
195-196 oC
Pelazid
H2O Solubility
20 mg/ml (HCl salt)
Pelazid
State
Solid
Pelazid
LogP
2.868
Pelazid
Dosage Forms
Liquid; Tablet
Pelazid
Indication
For the management of hypertension.
Pelazid
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Pelazid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Pelazid
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Pelazid
Patient Information
Pelazid
Organisms Affected
Humans and other mammals