Hycozid
Brand names,
Hycozid
Analogs
Hycozid
Brand Names Mixture
Hycozid
Chemical_Formula
C19H24N2O3
Hycozid
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Hycozid
fda sheet
Hycozid
msds (material safety sheet)
Hycozid
Synthesis Reference
No information avaliable
Hycozid
Molecular Weight
328.406 g/mol
Hycozid
Melting Point
195-196 oC
Hycozid
H2O Solubility
20 mg/ml (HCl salt)
Hycozid
State
Solid
Hycozid
LogP
2.868
Hycozid
Dosage Forms
Liquid; Tablet
Hycozid
Indication
For the management of hypertension.
Hycozid
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Hycozid
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Hycozid
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Hycozid
Patient Information
Hycozid
Organisms Affected
Humans and other mammals