Armazide
Brand names,
Armazide
Analogs
Armazide
Brand Names Mixture
Armazide
Chemical_Formula
C19H24N2O3
Armazide
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Armazide
fda sheet
Armazide
msds (material safety sheet)
Armazide
Synthesis Reference
No information avaliable
Armazide
Molecular Weight
328.406 g/mol
Armazide
Melting Point
195-196 oC
Armazide
H2O Solubility
20 mg/ml (HCl salt)
Armazide
State
Solid
Armazide
LogP
2.868
Armazide
Dosage Forms
Liquid; Tablet
Armazide
Indication
For the management of hypertension.
Armazide
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Armazide
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Armazide
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Armazide
Patient Information
Armazide
Organisms Affected
Humans and other mammals