Tekazin
Brand names,
Tekazin
Analogs
Tekazin
Brand Names Mixture
Tekazin
Chemical_Formula
C19H24N2O3
Tekazin
RX_link
http://www.rxlist.com/cgi/generic2/labet.htm
Tekazin
fda sheet
Tekazin
msds (material safety sheet)
Tekazin
Synthesis Reference
No information avaliable
Tekazin
Molecular Weight
328.406 g/mol
Tekazin
Melting Point
195-196 oC
Tekazin
H2O Solubility
20 mg/ml (HCl salt)
Tekazin
State
Solid
Tekazin
LogP
2.868
Tekazin
Dosage Forms
Liquid; Tablet
Tekazin
Indication
For the management of hypertension.
Tekazin
Pharmacology
Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.
Tekazin
Absorption
Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.
Tekazin
side effects and Toxicity
LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue
Tekazin
Patient Information
Tekazin
Organisms Affected
Humans and other mammals