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HIA Brand names, HIA Analogs

HIA Brand Names Mixture

  • No information avaliable

HIA Chemical_Formula

C19H24N2O3

HIA RX_link

http://www.rxlist.com/cgi/generic2/labet.htm

HIA fda sheet

HIA FDA

HIA msds (material safety sheet)

HIA MSDS

HIA Synthesis Reference

No information avaliable

HIA Molecular Weight

328.406 g/mol

HIA Melting Point

195-196 oC

HIA H2O Solubility

20 mg/ml (HCl salt)

HIA State

Solid

HIA LogP

2.868

HIA Dosage Forms

Liquid; Tablet

HIA Indication

For the management of hypertension.

HIA Pharmacology

Labetalol is an alpha-1 and beta adrenergic blocker used to treat high blood pressure. It works by blocking these adrenergic receptors, which slows sinus heart rate, decreases peripheral vascular resistance, and decreases cardiac output.

HIA Absorption

Completely absorbed (100%) from the gastrointestinal tract with peak plasma levels occurring 1 to 2 hours after oral administration. The absolute bioavailability of labetalol is increased when administered with food.

HIA side effects and Toxicity

LD50 = 66 mg/kg (Rat, IV). Side effects or adverse reactions include dizziness when standing up, very low blood pressure, severely slow heartbeat, weakness, diminished sexual function, fatigue

HIA Patient Information

HIA Organisms Affected

Humans and other mammals