GLAXO INC -- LABETALOL HYDROCHLORIDE -- 6505-01-244-7982
===================== Product Identification =====================
Product ID:LABETALOL HYDROCHLORIDE
MSDS Date:10/01/1988
FSC:6505
NIIN:01-244-7982
MSDS Number: BWLHM
=== Responsible Party ===
Company Name:GLAXO INC
Address:5 MOORE DR
City:RESEARCH TRIANGLE PARK
State:NC
ZIP:27709
Country:US
Info Phone Num:919-248-2354
Emergency Phone Num:919-248-2100/2700
CAGE:34006
=== Contractor Identification ===
Company Name:GLAXO WELLCOME INC.
Address:5 MOORE DR
Box:13398
City:DURHAM
State:NC
ZIP:27709
Country:US
Phone:919-248-2100
CAGE:34006
============= Composition/Information on Ingredients =============
Ingred Name:LABETALOL HYDROCHLORIDE
CAS:37780-64-6
Fraction by Wt: 100% %
Other REC Limits:NONE RECOMMENDED
ACGIH TLV:200 UG/M3
===================== Hazards Identification =====================
LD50 LC50 Mixture:GLAXO SAFE WORKING LEVEL: 2 MG/M3
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:IRRITATION TO NOSE, THROAT AND LUNGS.
PROLONGED INHALATION MAY RESULT IN INFLAMMATION, NOSE BLEEDS AND
PAINFUL BREATHING. SKIN CONTACT MAY CAUSE IRRITATION. PROLONGED
SKIN CONTACT MAY CAUSE INFLAMMATI ON RESULTING IN RASHES. EYE
CONTACT CAUSES IRRITATION. INGESTION MAY CAUSE LOWERING OF THE
BLOOD PRESSURE, DIZZINESS.
Explanation of Carcinogenicity:THIS COMPOUND CONTAINS NO INGREDIENTS AT
CONCENTRATIONS OF 0.1% OR GREATER THAT ARE CARCINOGENS OR SUSPECT
CARCINOGENS.
Effects of Overexposure:EYE IRRITATION, SKIN IRRITATION, SKIN RASHS,
UPPER RESPIRATORY TRACT IRRITATION, NAUSEA, VOMITING, FATIGUE,
DIZZINESS, LOWERING OF BLOOD PRESSURE.
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.
======================= First Aid Measures =======================
First Aid:EYES: FLUSH WITH WATER FOR 15 MINUTES WHILE HOLDING EYELIDS
OPEN. GET MEDICAL ATTENTION. SKIN: REMOVE CONTAMINATED CLOTHING.
WASH WITH SOAP AND WATER. IF IRRITATION PERSISTS, GET MEDICAL
ATTENTION. IN HALATION: REMOVE TO FRESH AIR. RESTORE BREATHING. GET
MEDICAL ATTENTION. INGESTION: GIVE COPIOUS AMOUNTS OF WATER AND
INDUCE VOMITING, IF CONSCIOUS. GET MEDICAL ATTENTION.
===================== Fire Fighting Measures =====================
Flash Point:NONFLAMMABLE
Lower Limits:NOT GIVEN
Upper Limits:NOT GIVEN
Extinguishing Media:WATERSPRAY, DRY CHEMICAL, FOAM
Fire Fighting Procedures:FIRE FIGHTERS SHOULD USE NIOSH APPROVED SCBA &
FULL PROTECTIVE EQUIPMENT WHEN FIGHTING CHEMICAL FIRE. USE WATER
SPRAY TO COOL NEARBY CONTAINERS EXPOSED TO FIRE.
Unusual Fire/Explosion Hazard:AS WITH ANY ORGANIC DUST, THERE IS
POTENTIAL FOR EXPLOSION WHEN SUSPENDED IN AIR IN HIGH
CONCENTRATIONS.
================== Accidental Release Measures ==================
Spill Release Procedures:NOTIFY SUPERVISOR. MINIMIZE CONTACT WITH
SPILLED MATERIAL. USE PROPER PERSONAL PROTECTIVE EQUIPMENT. CONTAIN
SPILL. STOP LEAK IF CAN DO SO WITHOUT RISK. ABSORB LIQUID WITH
SUITABLE ABSORBENT MATERIAL. COLLECT FOR DISPOSAL.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.
====================== Handling and Storage ======================
Handling and Storage Precautions:STORE IN A COOL, DRY, WELL-VENTILATED
AREA. USE STORAGE PRACTICES THAT WILL MINIMIZE THE GENERATION OF
DUST.
Other Precautions:AVOID SKIN CONTACT. LAUNDER CONTAMINATED CLOTHING
BEFORE REUSE.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:NONE FOR CONSUMER PACKAGE, A HALF MASK
RESPIRATOR WITH ORGANIC VAPOR/ACID GAS/HIGH EFFIENCY CARTRIDGES MAY
BE USED FOR HANDLING THE MATERIAL IN BULK.
Ventilation:LOCAL EXHAUST AND MECHANICAL (GENERAL) VENTILATION TO
MAINTAIN EXPOSURE LEVELS.
Protective Gloves:LATEX FOR BULK HANDLING
Eye Protection:SAFETY GLASSES OR GOGGLES
Other Protective Equipment:AN EMERGENCY EYE WASH STATION AND SHOWER
SHOULD BE AVAILABLE.
Work Hygienic Practices:WASH WITH SOAP AND WATER AFTER HANDLING PRODUCT
AND BEFORE EATING DRINKING OR SMOKING.
Supplemental Safety and Health
NONE SPECIFIED BY MANUFACTURER.
================== Physical/Chemical Properties ==================
HCC:N1
Boiling Pt:B.P. Text:NOT GIVEN
Melt/Freeze Pt:M.P/F.P Text:356F,180C
Vapor Pres:NOT GIVEN
Vapor Density:NOT GIVEN
Spec Gravity:NOT GIVEN
Evaporation Rate & Reference:NOT GIVEN
Solubility in Water:NOT GIVEN
Appearance and Odor:WHITE OR OFF-WHITE CRYSTALLINE POWDER
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
NONE SPECIFIED BY MANUFACTURER.
Stability Condition to Avoid:HEAT, OPEN FLAME, HIGH TEMPERATURES
Hazardous Decomposition Products:TOXIC AND/OR CORROSIVE VAPORS
CONSISTING OF HYDROGEN CHLORIDE AND OXIDES OF NITROGEN.
==================== Disposal Considerations ====================
Waste Disposal Methods:PREVENT WASTE FROM CONTAMINATING SURROUNDING
ENVIRONMENT. DISCARD ANY PRODUCT, RESIDUE, DISPOSAL CONTAINER OR
LINER IN ACCORDANCE WITH ALL FEDERAL, STATE AND LOCAL REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.