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Nifedipine Brand names, Nifedipine Analogs

Nifedipine Brand Names Mixture

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Nifedipine Chemical_Formula


Nifedipine RX_link

Nifedipine fda sheet

Nifedipine FDA

Nifedipine msds (material safety sheet)

Nifedipine MSDS

Nifedipine Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifedipine Molecular Weight

346.335 g/mol

Nifedipine Melting Point

172 - 174 oC

Nifedipine H2O Solubility


Nifedipine State


Nifedipine LogP


Nifedipine Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifedipine Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifedipine Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifedipine Absorption

Rapidly and fully absorbed following oral administration.

Nifedipine side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifedipine Patient Information

Nifedipine Organisms Affected

Humans and other mammals