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Aldipin Brand names, Aldipin Analogs

Aldipin Brand Names Mixture

  • No information avaliable

Aldipin Chemical_Formula

C17H18N2O6

Aldipin RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Aldipin fda sheet

Aldipin FDA

Aldipin msds (material safety sheet)

Aldipin MSDS

Aldipin Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Aldipin Molecular Weight

346.335 g/mol

Aldipin Melting Point

172 - 174 oC

Aldipin H2O Solubility

Insoluble

Aldipin State

Solid

Aldipin LogP

2.343

Aldipin Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Aldipin Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Aldipin Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Aldipin Absorption

Rapidly and fully absorbed following oral administration.

Aldipin side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Aldipin Patient Information

Aldipin Organisms Affected

Humans and other mammals