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Duranifin Brand names, Duranifin Analogs

Duranifin Brand Names Mixture

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Duranifin Chemical_Formula


Duranifin RX_link


Duranifin fda sheet

Duranifin FDA

Duranifin msds (material safety sheet)

Duranifin MSDS

Duranifin Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Duranifin Molecular Weight

346.335 g/mol

Duranifin Melting Point

172 - 174 oC

Duranifin H2O Solubility


Duranifin State


Duranifin LogP


Duranifin Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Duranifin Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Duranifin Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Duranifin Absorption

Rapidly and fully absorbed following oral administration.

Duranifin side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Duranifin Patient Information

Duranifin Organisms Affected

Humans and other mammals