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Nedipin Brand names, Nedipin Analogs

Nedipin Brand Names Mixture

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Nedipin Chemical_Formula


Nedipin RX_link

Nedipin fda sheet

Nedipin FDA

Nedipin msds (material safety sheet)

Nedipin MSDS

Nedipin Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nedipin Molecular Weight

346.335 g/mol

Nedipin Melting Point

172 - 174 oC

Nedipin H2O Solubility


Nedipin State


Nedipin LogP


Nedipin Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nedipin Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nedipin Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nedipin Absorption

Rapidly and fully absorbed following oral administration.

Nedipin side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nedipin Patient Information

Nedipin Organisms Affected

Humans and other mammals