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Nifedicor Brand names, Nifedicor Analogs

Nifedicor Brand Names Mixture

  • No information avaliable

Nifedicor Chemical_Formula

C17H18N2O6

Nifedicor RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Nifedicor fda sheet

Nifedicor FDA

Nifedicor msds (material safety sheet)

Nifedicor MSDS

Nifedicor Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifedicor Molecular Weight

346.335 g/mol

Nifedicor Melting Point

172 - 174 oC

Nifedicor H2O Solubility

Insoluble

Nifedicor State

Solid

Nifedicor LogP

2.343

Nifedicor Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifedicor Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifedicor Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifedicor Absorption

Rapidly and fully absorbed following oral administration.

Nifedicor side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifedicor Patient Information

Nifedicor Organisms Affected

Humans and other mammals