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Tibricol Brand names, Tibricol Analogs

Tibricol Brand Names Mixture

  • No information avaliable

Tibricol Chemical_Formula

C17H18N2O6

Tibricol RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Tibricol fda sheet

Tibricol FDA

Tibricol msds (material safety sheet)

Tibricol MSDS

Tibricol Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Tibricol Molecular Weight

346.335 g/mol

Tibricol Melting Point

172 - 174 oC

Tibricol H2O Solubility

Insoluble

Tibricol State

Solid

Tibricol LogP

2.343

Tibricol Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Tibricol Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Tibricol Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Tibricol Absorption

Rapidly and fully absorbed following oral administration.

Tibricol side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Tibricol Patient Information

Tibricol Organisms Affected

Humans and other mammals