Adalat Oros

Adalat Oros Brand names, Adalat Oros Analogs

Adalat Oros Brand Names Mixture

No information avaliable

Adalat Oros Chemical_Formula

C₁₇H₁₈N₂O₆

Adalat Oros RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adalat Oros fda sheet

Adalat_Oros FDA

Adalat Oros msds (material safety sheet)

Adalat_Oros MSDS

Adalat Oros Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat Oros Molecular Weight

346.335 g/mol

Adalat Oros Melting Point

172 - 174 ^oC

Adalat Oros H₂O Solubility

Insoluble

Adalat Oros State

Solid

Adalat Oros LogP

2.343

Adalat Oros Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat Oros Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat Oros Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat Oros Absorption

Rapidly and fully absorbed following oral administration.

Adalat Oros side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Adalat Oros Patient Information

Adalat Oros Organisms Affected

Humans and other mammals