Adalat 20

Adalat 20 Brand names, Adalat 20 Analogs

Adalat 20 Brand Names Mixture

No information avaliable

Adalat 20 Chemical_Formula

C₁₇H₁₈N₂O₆

Adalat 20 RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adalat 20 fda sheet

Adalat_20 FDA

Adalat 20 msds (material safety sheet)

Adalat_20 MSDS

Adalat 20 Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat 20 Molecular Weight

346.335 g/mol

Adalat 20 Melting Point

172 - 174 ^oC

Adalat 20 H₂O Solubility

Insoluble

Adalat 20 State

Solid

Adalat 20 LogP

2.343

Adalat 20 Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat 20 Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat 20 Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat 20 Absorption

Rapidly and fully absorbed following oral administration.

Adalat 20 side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Adalat 20 Patient Information

Adalat 20 Organisms Affected

Humans and other mammals