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Corynphar Brand names, Corynphar Analogs

Corynphar Brand Names Mixture

  • No information avaliable

Corynphar Chemical_Formula


Corynphar RX_link

Corynphar fda sheet

Corynphar FDA

Corynphar msds (material safety sheet)

Corynphar MSDS

Corynphar Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Corynphar Molecular Weight

346.335 g/mol

Corynphar Melting Point

172 - 174 oC

Corynphar H2O Solubility


Corynphar State


Corynphar LogP


Corynphar Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Corynphar Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Corynphar Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Corynphar Absorption

Rapidly and fully absorbed following oral administration.

Corynphar side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Corynphar Patient Information

Corynphar Organisms Affected

Humans and other mammals