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Cordaflex Brand names, Cordaflex Analogs

Cordaflex Brand Names Mixture

  • No information avaliable

Cordaflex Chemical_Formula

C17H18N2O6

Cordaflex RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Cordaflex fda sheet

Cordaflex FDA

Cordaflex msds (material safety sheet)

Cordaflex MSDS

Cordaflex Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Cordaflex Molecular Weight

346.335 g/mol

Cordaflex Melting Point

172 - 174 oC

Cordaflex H2O Solubility

Insoluble

Cordaflex State

Solid

Cordaflex LogP

2.343

Cordaflex Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Cordaflex Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Cordaflex Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Cordaflex Absorption

Rapidly and fully absorbed following oral administration.

Cordaflex side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Cordaflex Patient Information

Cordaflex Organisms Affected

Humans and other mammals