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Cordafen Brand names, Cordafen Analogs

Cordafen Brand Names Mixture

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Cordafen Chemical_Formula


Cordafen RX_link

Cordafen fda sheet

Cordafen FDA

Cordafen msds (material safety sheet)

Cordafen MSDS

Cordafen Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Cordafen Molecular Weight

346.335 g/mol

Cordafen Melting Point

172 - 174 oC

Cordafen H2O Solubility


Cordafen State


Cordafen LogP


Cordafen Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Cordafen Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Cordafen Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Cordafen Absorption

Rapidly and fully absorbed following oral administration.

Cordafen side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Cordafen Patient Information

Cordafen Organisms Affected

Humans and other mammals