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Nifedine Brand names, Nifedine Analogs

Nifedine Brand Names Mixture

  • No information avaliable

Nifedine Chemical_Formula


Nifedine RX_link

Nifedine fda sheet

Nifedine FDA

Nifedine msds (material safety sheet)

Nifedine MSDS

Nifedine Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifedine Molecular Weight

346.335 g/mol

Nifedine Melting Point

172 - 174 oC

Nifedine H2O Solubility


Nifedine State


Nifedine LogP


Nifedine Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifedine Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifedine Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifedine Absorption

Rapidly and fully absorbed following oral administration.

Nifedine side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifedine Patient Information

Nifedine Organisms Affected

Humans and other mammals