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Fenamon Brand names, Fenamon Analogs

Fenamon Brand Names Mixture

  • No information avaliable

Fenamon Chemical_Formula

C17H18N2O6

Fenamon RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Fenamon fda sheet

Fenamon FDA

Fenamon msds (material safety sheet)

Fenamon MSDS

Fenamon Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Fenamon Molecular Weight

346.335 g/mol

Fenamon Melting Point

172 - 174 oC

Fenamon H2O Solubility

Insoluble

Fenamon State

Solid

Fenamon LogP

2.343

Fenamon Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Fenamon Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Fenamon Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Fenamon Absorption

Rapidly and fully absorbed following oral administration.

Fenamon side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Fenamon Patient Information

Fenamon Organisms Affected

Humans and other mammals