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Adapress Brand names, Adapress Analogs

Adapress Brand Names Mixture

  • No information avaliable

Adapress Chemical_Formula

C17H18N2O6

Adapress RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adapress fda sheet

Adapress FDA

Adapress msds (material safety sheet)

Adapress MSDS

Adapress Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adapress Molecular Weight

346.335 g/mol

Adapress Melting Point

172 - 174 oC

Adapress H2O Solubility

Insoluble

Adapress State

Solid

Adapress LogP

2.343

Adapress Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adapress Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adapress Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adapress Absorption

Rapidly and fully absorbed following oral administration.

Adapress side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Adapress Patient Information

Adapress Organisms Affected

Humans and other mammals