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Nifelan Brand names, Nifelan Analogs

Nifelan Brand Names Mixture

  • No information avaliable

Nifelan Chemical_Formula

C17H18N2O6

Nifelan RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Nifelan fda sheet

Nifelan FDA

Nifelan msds (material safety sheet)

Nifelan MSDS

Nifelan Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifelan Molecular Weight

346.335 g/mol

Nifelan Melting Point

172 - 174 oC

Nifelan H2O Solubility

Insoluble

Nifelan State

Solid

Nifelan LogP

2.343

Nifelan Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifelan Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifelan Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifelan Absorption

Rapidly and fully absorbed following oral administration.

Nifelan side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifelan Patient Information

Nifelan Organisms Affected

Humans and other mammals