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Alonix S Brand names, Alonix S Analogs

Alonix S Brand Names Mixture

  • No information avaliable

Alonix S Chemical_Formula

C17H18N2O6

Alonix S RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Alonix S fda sheet

Alonix_S FDA

Alonix S msds (material safety sheet)

Alonix_S MSDS

Alonix S Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Alonix S Molecular Weight

346.335 g/mol

Alonix S Melting Point

172 - 174 oC

Alonix S H2O Solubility

Insoluble

Alonix S State

Solid

Alonix S LogP

2.343

Alonix S Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Alonix S Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Alonix S Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Alonix S Absorption

Rapidly and fully absorbed following oral administration.

Alonix S side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Alonix S Patient Information

Alonix S Organisms Affected

Humans and other mammals