Nifedipine Retard

Nifedipine Retard Brand names, Nifedipine Retard Analogs

Nifedipine Retard Brand Names Mixture

No information avaliable

Nifedipine Retard Chemical_Formula

C₁₇H₁₈N₂O₆

Nifedipine Retard RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Nifedipine Retard fda sheet

Nifedipine_Retard FDA

Nifedipine Retard msds (material safety sheet)

Nifedipine_Retard MSDS

Nifedipine Retard Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifedipine Retard Molecular Weight

346.335 g/mol

Nifedipine Retard Melting Point

172 - 174 ^oC

Nifedipine Retard H₂O Solubility

Insoluble

Nifedipine Retard State

Solid

Nifedipine Retard LogP

2.343

Nifedipine Retard Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifedipine Retard Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifedipine Retard Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifedipine Retard Absorption

Rapidly and fully absorbed following oral administration.

Nifedipine Retard side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Nifedipine Retard Patient Information

Nifedipine Retard Organisms Affected

Humans and other mammals