Cardilat

Cardilat Brand names, Cardilat Analogs

Cardilat Brand Names Mixture

No information avaliable

Cardilat Chemical_Formula

C₁₇H₁₈N₂O₆

Cardilat RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Cardilat fda sheet

Cardilat FDA

Cardilat msds (material safety sheet)

Cardilat MSDS

Cardilat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Cardilat Molecular Weight

346.335 g/mol

Cardilat Melting Point

172 - 174 ^oC

Cardilat H₂O Solubility

Insoluble

Cardilat State

Solid

Cardilat LogP

2.343

Cardilat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Cardilat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Cardilat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Cardilat Absorption

Rapidly and fully absorbed following oral administration.

Cardilat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Cardilat Patient Information

Cardilat Organisms Affected

Humans and other mammals