Adalat 10

Adalat 10 Brand names, Adalat 10 Analogs

Adalat 10 Brand Names Mixture

No information avaliable

Adalat 10 Chemical_Formula

C₁₇H₁₈N₂O₆

Adalat 10 RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adalat 10 fda sheet

Adalat_10 FDA

Adalat 10 msds (material safety sheet)

Adalat_10 MSDS

Adalat 10 Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat 10 Molecular Weight

346.335 g/mol

Adalat 10 Melting Point

172 - 174 ^oC

Adalat 10 H₂O Solubility

Insoluble

Adalat 10 State

Solid

Adalat 10 LogP

2.343

Adalat 10 Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat 10 Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat 10 Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat 10 Absorption

Rapidly and fully absorbed following oral administration.

Adalat 10 side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Adalat 10 Patient Information

Adalat 10 Organisms Affected

Humans and other mammals