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Nifelate Brand names, Nifelate Analogs

Nifelate Brand Names Mixture

  • No information avaliable

Nifelate Chemical_Formula


Nifelate RX_link

Nifelate fda sheet

Nifelate FDA

Nifelate msds (material safety sheet)

Nifelate MSDS

Nifelate Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifelate Molecular Weight

346.335 g/mol

Nifelate Melting Point

172 - 174 oC

Nifelate H2O Solubility


Nifelate State


Nifelate LogP


Nifelate Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifelate Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifelate Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifelate Absorption

Rapidly and fully absorbed following oral administration.

Nifelate side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifelate Patient Information

Nifelate Organisms Affected

Humans and other mammals