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Nifecard Brand names, Nifecard Analogs

Nifecard Brand Names Mixture

  • No information avaliable

Nifecard Chemical_Formula

C17H18N2O6

Nifecard RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Nifecard fda sheet

Nifecard FDA

Nifecard msds (material safety sheet)

Nifecard MSDS

Nifecard Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifecard Molecular Weight

346.335 g/mol

Nifecard Melting Point

172 - 174 oC

Nifecard H2O Solubility

Insoluble

Nifecard State

Solid

Nifecard LogP

2.343

Nifecard Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifecard Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifecard Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifecard Absorption

Rapidly and fully absorbed following oral administration.

Nifecard side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifecard Patient Information

Nifecard Organisms Affected

Humans and other mammals