Nifedirex LP en es it fr

Nifedirex LP Brand names, Nifedirex LP Analogs

Nifedirex LP Brand Names Mixture

  • No information avaliable

Nifedirex LP Chemical_Formula


Nifedirex LP RX_link

Nifedirex LP fda sheet

Nifedirex_LP FDA

Nifedirex LP msds (material safety sheet)

Nifedirex_LP MSDS

Nifedirex LP Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifedirex LP Molecular Weight

346.335 g/mol

Nifedirex LP Melting Point

172 - 174 oC

Nifedirex LP H2O Solubility


Nifedirex LP State


Nifedirex LP LogP


Nifedirex LP Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifedirex LP Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifedirex LP Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifedirex LP Absorption

Rapidly and fully absorbed following oral administration.

Nifedirex LP side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifedirex LP Patient Information

Nifedirex LP Organisms Affected

Humans and other mammals