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Sepamit Brand names, Sepamit Analogs

Sepamit Brand Names Mixture

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Sepamit Chemical_Formula


Sepamit RX_link

Sepamit fda sheet

Sepamit FDA

Sepamit msds (material safety sheet)

Sepamit MSDS

Sepamit Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Sepamit Molecular Weight

346.335 g/mol

Sepamit Melting Point

172 - 174 oC

Sepamit H2O Solubility


Sepamit State


Sepamit LogP


Sepamit Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Sepamit Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Sepamit Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Sepamit Absorption

Rapidly and fully absorbed following oral administration.

Sepamit side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Sepamit Patient Information

Sepamit Organisms Affected

Humans and other mammals