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Angipec Brand names, Angipec Analogs

Angipec Brand Names Mixture

  • No information avaliable

Angipec Chemical_Formula

C17H18N2O6

Angipec RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Angipec fda sheet

Angipec FDA

Angipec msds (material safety sheet)

Angipec MSDS

Angipec Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Angipec Molecular Weight

346.335 g/mol

Angipec Melting Point

172 - 174 oC

Angipec H2O Solubility

Insoluble

Angipec State

Solid

Angipec LogP

2.343

Angipec Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Angipec Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Angipec Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Angipec Absorption

Rapidly and fully absorbed following oral administration.

Angipec side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Angipec Patient Information

Angipec Organisms Affected

Humans and other mammals