Adalat CR

Adalat CR Brand names, Adalat CR Analogs

Adalat CR Brand Names Mixture

No information avaliable

Adalat CR Chemical_Formula

C₁₇H₁₈N₂O₆

Adalat CR RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adalat CR fda sheet

Adalat_CR FDA

Adalat CR msds (material safety sheet)

Adalat_CR MSDS

Adalat CR Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat CR Molecular Weight

346.335 g/mol

Adalat CR Melting Point

172 - 174 ^oC

Adalat CR H₂O Solubility

Insoluble

Adalat CR State

Solid

Adalat CR LogP

2.343

Adalat CR Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat CR Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat CR Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat CR Absorption

Rapidly and fully absorbed following oral administration.

Adalat CR side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Adalat CR Patient Information

Adalat CR Organisms Affected

Humans and other mammals