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Adalat CR Brand names, Adalat CR Analogs

Adalat CR Brand Names Mixture

  • No information avaliable

Adalat CR Chemical_Formula


Adalat CR RX_link

Adalat CR fda sheet

Adalat_CR FDA

Adalat CR msds (material safety sheet)

Adalat_CR MSDS

Adalat CR Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat CR Molecular Weight

346.335 g/mol

Adalat CR Melting Point

172 - 174 oC

Adalat CR H2O Solubility


Adalat CR State


Adalat CR LogP


Adalat CR Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat CR Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat CR Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat CR Absorption

Rapidly and fully absorbed following oral administration.

Adalat CR side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Adalat CR Patient Information

Adalat CR Organisms Affected

Humans and other mammals