Adalat Retard

Adalat Retard Brand names, Adalat Retard Analogs

Adalat Retard Brand Names Mixture

No information avaliable

Adalat Retard Chemical_Formula

C₁₇H₁₈N₂O₆

Adalat Retard RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adalat Retard fda sheet

Adalat_Retard FDA

Adalat Retard msds (material safety sheet)

Adalat_Retard MSDS

Adalat Retard Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat Retard Molecular Weight

346.335 g/mol

Adalat Retard Melting Point

172 - 174 ^oC

Adalat Retard H₂O Solubility

Insoluble

Adalat Retard State

Solid

Adalat Retard LogP

2.343

Adalat Retard Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat Retard Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat Retard Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat Retard Absorption

Rapidly and fully absorbed following oral administration.

Adalat Retard side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Adalat Retard Patient Information

Adalat Retard Organisms Affected

Humans and other mammals