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Corotrend Brand names, Corotrend Analogs

Corotrend Brand Names Mixture

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Corotrend Chemical_Formula


Corotrend RX_link

Corotrend fda sheet

Corotrend FDA

Corotrend msds (material safety sheet)

Corotrend MSDS

Corotrend Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Corotrend Molecular Weight

346.335 g/mol

Corotrend Melting Point

172 - 174 oC

Corotrend H2O Solubility


Corotrend State


Corotrend LogP


Corotrend Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Corotrend Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Corotrend Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Corotrend Absorption

Rapidly and fully absorbed following oral administration.

Corotrend side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Corotrend Patient Information

Corotrend Organisms Affected

Humans and other mammals