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Hexadilat Brand names, Hexadilat Analogs

Hexadilat Brand Names Mixture

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Hexadilat Chemical_Formula


Hexadilat RX_link


Hexadilat fda sheet

Hexadilat FDA

Hexadilat msds (material safety sheet)

Hexadilat MSDS

Hexadilat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Hexadilat Molecular Weight

346.335 g/mol

Hexadilat Melting Point

172 - 174 oC

Hexadilat H2O Solubility


Hexadilat State


Hexadilat LogP


Hexadilat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Hexadilat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Hexadilat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Hexadilat Absorption

Rapidly and fully absorbed following oral administration.

Hexadilat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Hexadilat Patient Information

Hexadilat Organisms Affected

Humans and other mammals