Alat en es it fr

Alat Brand names, Alat Analogs

Alat Brand Names Mixture

  • No information avaliable

Alat Chemical_Formula


Alat RX_link

Alat fda sheet

Alat FDA

Alat msds (material safety sheet)


Alat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Alat Molecular Weight

346.335 g/mol

Alat Melting Point

172 - 174 oC

Alat H2O Solubility


Alat State


Alat LogP


Alat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Alat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Alat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Alat Absorption

Rapidly and fully absorbed following oral administration.

Alat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Alat Patient Information

Alat Organisms Affected

Humans and other mammals