Adalat LA

Adalat LA Brand names, Adalat LA Analogs

Adalat LA Brand Names Mixture

No information avaliable

Adalat LA Chemical_Formula

C₁₇H₁₈N₂O₆

Adalat LA RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adalat LA fda sheet

Adalat_LA FDA

Adalat LA msds (material safety sheet)

Adalat_LA MSDS

Adalat LA Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat LA Molecular Weight

346.335 g/mol

Adalat LA Melting Point

172 - 174 ^oC

Adalat LA H₂O Solubility

Insoluble

Adalat LA State

Solid

Adalat LA LogP

2.343

Adalat LA Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat LA Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat LA Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat LA Absorption

Rapidly and fully absorbed following oral administration.

Adalat LA side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Adalat LA Patient Information

Adalat LA Organisms Affected

Humans and other mammals