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Anpine Brand names, Anpine Analogs

Anpine Brand Names Mixture

  • No information avaliable

Anpine Chemical_Formula


Anpine RX_link

Anpine fda sheet

Anpine FDA

Anpine msds (material safety sheet)

Anpine MSDS

Anpine Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Anpine Molecular Weight

346.335 g/mol

Anpine Melting Point

172 - 174 oC

Anpine H2O Solubility


Anpine State


Anpine LogP


Anpine Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Anpine Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Anpine Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Anpine Absorption

Rapidly and fully absorbed following oral administration.

Anpine side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Anpine Patient Information

Anpine Organisms Affected

Humans and other mammals