PharmacyCodes



Coral en es it fr

Coral Brand names, Coral Analogs

Coral Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Coral Chemical_Formula

C13H22N4O3S

Coral RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Coral fda sheet

Coral FDA

Coral msds (material safety sheet)

Coral MSDS

Coral Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Coral Molecular Weight

314.405 g/mol

Coral Melting Point

69-70 oC

Coral H2O Solubility

24.7 mg/mL

Coral State

Solid

Coral LogP

1.93

Coral Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Coral Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Coral Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Coral Absorption

Approximately 50% bioavailability orally.

Coral side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Coral Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Coral Organisms Affected

Humans and other mammals