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Nifedepat Brand names, Nifedepat Analogs

Nifedepat Brand Names Mixture

  • No information avaliable

Nifedepat Chemical_Formula


Nifedepat RX_link

Nifedepat fda sheet

Nifedepat FDA

Nifedepat msds (material safety sheet)

Nifedepat MSDS

Nifedepat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifedepat Molecular Weight

346.335 g/mol

Nifedepat Melting Point

172 - 174 oC

Nifedepat H2O Solubility


Nifedepat State


Nifedepat LogP


Nifedepat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifedepat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifedepat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifedepat Absorption

Rapidly and fully absorbed following oral administration.

Nifedepat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Nifedepat Patient Information

Nifedepat Organisms Affected

Humans and other mammals