Adalat PA

Adalat PA Brand names, Adalat PA Analogs

Adalat PA Brand Names Mixture

No information avaliable

Adalat PA Chemical_Formula

C₁₇H₁₈N₂O₆

Adalat PA RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Adalat PA fda sheet

Adalat_PA FDA

Adalat PA msds (material safety sheet)

Adalat_PA MSDS

Adalat PA Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Adalat PA Molecular Weight

346.335 g/mol

Adalat PA Melting Point

172 - 174 ^oC

Adalat PA H₂O Solubility

Insoluble

Adalat PA State

Solid

Adalat PA LogP

2.343

Adalat PA Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Adalat PA Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Adalat PA Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Adalat PA Absorption

Rapidly and fully absorbed following oral administration.

Adalat PA side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Adalat PA Patient Information

Adalat PA Organisms Affected

Humans and other mammals