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Dignokonstant Brand names, Dignokonstant Analogs

Dignokonstant Brand Names Mixture

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Dignokonstant Chemical_Formula


Dignokonstant RX_link


Dignokonstant fda sheet

Dignokonstant FDA

Dignokonstant msds (material safety sheet)

Dignokonstant MSDS

Dignokonstant Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Dignokonstant Molecular Weight

346.335 g/mol

Dignokonstant Melting Point

172 - 174 oC

Dignokonstant H2O Solubility


Dignokonstant State


Dignokonstant LogP


Dignokonstant Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Dignokonstant Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Dignokonstant Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Dignokonstant Absorption

Rapidly and fully absorbed following oral administration.

Dignokonstant side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Dignokonstant Patient Information

Dignokonstant Organisms Affected

Humans and other mammals