Macorel en es it fr

Macorel Brand names, Macorel Analogs

Macorel Brand Names Mixture

  • No information avaliable

Macorel Chemical_Formula


Macorel RX_link

Macorel fda sheet

Macorel FDA

Macorel msds (material safety sheet)

Macorel MSDS

Macorel Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Macorel Molecular Weight

346.335 g/mol

Macorel Melting Point

172 - 174 oC

Macorel H2O Solubility


Macorel State


Macorel LogP


Macorel Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Macorel Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Macorel Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Macorel Absorption

Rapidly and fully absorbed following oral administration.

Macorel side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Macorel Patient Information

Macorel Organisms Affected

Humans and other mammals