Nifelat

Nifelat Brand names, Nifelat Analogs

Nifelat Brand Names Mixture

No information avaliable

Nifelat Chemical_Formula

C₁₇H₁₈N₂O₆

Nifelat RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Nifelat fda sheet

Nifelat FDA

Nifelat msds (material safety sheet)

Nifelat MSDS

Nifelat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Nifelat Molecular Weight

346.335 g/mol

Nifelat Melting Point

172 - 174 ^oC

Nifelat H₂O Solubility

Insoluble

Nifelat State

Solid

Nifelat LogP

2.343

Nifelat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Nifelat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Nifelat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Nifelat Absorption

Rapidly and fully absorbed following oral administration.

Nifelat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD₅₀=494 mg/kg (orally in mice); LD₅₀=1022 mg/kg (orally in rats)

Nifelat Patient Information

Nifelat Organisms Affected

Humans and other mammals