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Pidilat Brand names, Pidilat Analogs

Pidilat Brand Names Mixture

  • No information avaliable

Pidilat Chemical_Formula

C17H18N2O6

Pidilat RX_link

http://www.rxlist.com/cgi/generic2/nifedip.htm

Pidilat fda sheet

Pidilat FDA

Pidilat msds (material safety sheet)

Pidilat MSDS

Pidilat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

Pidilat Molecular Weight

346.335 g/mol

Pidilat Melting Point

172 - 174 oC

Pidilat H2O Solubility

Insoluble

Pidilat State

Solid

Pidilat LogP

2.343

Pidilat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

Pidilat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

Pidilat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

Pidilat Absorption

Rapidly and fully absorbed following oral administration.

Pidilat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

Pidilat Patient Information

Pidilat Organisms Affected

Humans and other mammals