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N1fedilat Brand names, N1fedilat Analogs

N1fedilat Brand Names Mixture

  • No information avaliable

N1fedilat Chemical_Formula


N1fedilat RX_link


N1fedilat fda sheet

N1fedilat FDA

N1fedilat msds (material safety sheet)

N1fedilat MSDS

N1fedilat Synthesis Reference

Bossert, Vater, U.S. Pat. 3,485,847 (1969)

N1fedilat Molecular Weight

346.335 g/mol

N1fedilat Melting Point

172 - 174 oC

N1fedilat H2O Solubility


N1fedilat State


N1fedilat LogP


N1fedilat Dosage Forms

Capsule; Tablet; Tablet (extended-release)

N1fedilat Indication

For the management of vasospastic angina, chronic stable angina and hypertension.

N1fedilat Pharmacology

Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.

N1fedilat Absorption

Rapidly and fully absorbed following oral administration.

N1fedilat side effects and Toxicity

Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)

N1fedilat Patient Information

N1fedilat Organisms Affected

Humans and other mammals