Orix
Orix Brand names, Orix Analogs
- Adalat
- Adalat 10
- Adalat 20
- Adalat 5
- Adalat CC
- Adalat CR
- Adalat Crono
- Adalat Ft
- Adalat Gits
- Adalat Gits 30
- Adalat LA
- Adalat LP
- Adalat Oros
- Adalat PA
- Adalat Retard
- Adalate
- Adapine
- Adapress
- Alat
- Aldipin
- Alfadal
- Alonix
- Alonix S
- Alpha-Nifedipine Retard
- Angipec
- Anifed
- Anpine
- Apo-Nifed
- Aprical
- Bonacid
- Calcibloc
- Calcigard
- Calcilat
- Camont
- Cardifen
- Cardilat
- Cardilate
- Cardionorm
- Chronadalate
- Chronadalate Lp
- Citilat
- Coracten
- Coral
- Cordafen
- Cordaflex
- Cordalat
- Cordicant
- Cordilan
- Cordipin
- Corinfar
- Corotrend
- Corynphar
- Depin
- Dignokonstant
- Dilafed
- Dilcor
- Dipinkor
- Duranifin
- Ecodipi
- Ecodipin
- Ecodipin E
- Fedcor
- Fedcor Retard
- Fenamon
- Fenamon Sr
- Fenihidin
- Fenihidine
- Glopir
- Hadipin
- Hexadilat
- Introcar
- Kordafen
- Macorel
- Megalat
- Myogard
- N1fedilat
- Nedipin
- Nicardia
- Nifangin
- Nifar
- Nifdemin
- Nifebene
- Nifecard
- Nifecor
- Nifedepat
- Nifedicor
- Nifedin
- Nifedine
- Nifedipine Retard
- Nifedipres
- Nifedirex LP
- Nifelan
- Nifelat
- Nifelat Q
- Nifelate
- Nifensar XL
- Nificard
- Nifidine
- Nifipen
- Niphedipine
- Orix
- Oxcord
- Pidilat
- Procardia
- Procardia XL
- Sepamit
- Tibricol
- Zenusin
Orix Brand Names Mixture
- No information avaliable
Orix Chemical_Formula
C17H18N2O6
Orix RX_link
http://www.rxlist.com/cgi/generic2/nifedip.htm
Orix fda sheet
Orix msds (material safety sheet)
Orix Synthesis Reference
Bossert, Vater, U.S. Pat. 3,485,847 (1969)
Orix Molecular Weight
346.335 g/mol
Orix Melting Point
172 - 174 oC
Orix H2O Solubility
Insoluble
Orix State
Solid
Orix LogP
2.343
Orix Dosage Forms
Capsule; Tablet; Tablet (extended-release)
Orix Indication
For the management of vasospastic angina, chronic stable angina and hypertension.
Orix Pharmacology
Nifedipine, the prototype of the dihydropyridine class of calcium-channel antagonists, is similar to other dihydropyridines including amlodipine, felodipine, isradipine, and nicardipine. Nifedipine is used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon. By blocking the calcium channels, Nifedipine inhibits the spasm of the coronary artery and dilates the systemic arteries, results in a increase of myocardial oxygen supply and a decrease in systemic blood pressure.
Orix Absorption
Rapidly and fully absorbed following oral administration.
Orix side effects and Toxicity
Symptoms of overdose include dizziness, drowsiness, nausea, severe drop in blood pressure, slurred speech, and weakness. LD50=494 mg/kg (orally in mice); LD50=1022 mg/kg (orally in rats)
Orix Patient Information
Orix Organisms Affected
Humans and other mammals
